Huntington s Disease ( Hd ) - 1250 Words

Statement of Topic Huntington’s Disease (HD) is a genetic disorder in which the necrosis of cells in the brain causes early death [9]. The neurodegeneration of the brain leads to mechanical and psychological symptoms, which can present normally from 30 to 50 years of age or even earlier, which is referred to as Juvenile Huntington’s Disease [3,5,6]. Some mechanical symptoms of HD are change in gait, uncontrolled or sudden movement, abnormal face movement, turning the whole head instead of using the eyes, difficulty swallowing, impairment of speech and general decrease of motor skills [1]. Psychological symptoms include but are not limited to paranoia, irritability, mood swings, changes in behavior such as agitation or instability and†¦show more content†¦These factors can determine how well the brain will hold up against the physical deterioration of the disease. This could possibly lead to postponed and later onset or slower progression of HD [8]. Science and Methods Used Huntington’s Disease is dominant and autosomal, affecting chromosome 4 on the genome [3,7]. Normal individuals have that specific CAG strand repeated 10-28 times, however, an individual with HD possesses 36-100 repeats [1,3,7]. The methods in which cognitive and brain reserve were measured were through a series of cognitive tests and neuroimaging evaluation for six consecutive years. First of all, the participants were uniquely and specifically chosen, making sure they fit proper criteria. This included not possessing other mental or physical disabilities or complications such as depression, mental disabilities, cardiac or health issues and any metal implants (due to neuroimaging). The 821 participants were all over the age of 18, possessed at least 36 CAG repeats, and tested positive (for HD) and had a family history of HD. Initial tests were taken to set a baseline to compare results and the study consisted of six follow-up sessions. Due to unavoidable circumstances not all participants followed up annually for six years, which caused missing data as shown

The Dual Inheritance Within Christianity Of Greek And...

(1) Describe the dual inheritance within Christianity of Greek and Jewish thought. How were these traditions similar? How were they distinct? How did each contribute to the formation of Christian life and belief? Cite MacCulloch in your answer. Christianity has been heavily influenced by both Greek and Judaic traditions. As we said in class, â€Å"the first generations of Christians were Jews who lived in a world shaped by Greek elite culture† (Christianity The First Three Thousand Years MacCulloch 2). The Greeks and the Jews have many similarities. For example, both the Greeks and the Jewish peoples had their own sense of uniqueness, the Greeks with their tradition and culture being spread and adopted throughout the Eurasian and African continents, and the Jews believed they were an elect group of people chosen by God and having a special relationship with him. Both the Greeks and the Jews were also alphabetic cultures, something not common in that time. This allowed the two cultures to easily convey complex thoughts and ideas through a set of symbols rather than with pictograms that were popular with other cultures in that time period. And the final similarity between the Greek and Jewish traditions is how each culture was anchored in a text specific to them. The Greeks had The Iliad and The Odyssey by Homer, two books that became defining texts in the Greek tradition as well as a focal point of classic Greek ideals and values. However, the Judaic tradition focused on theShow MoreRelatedhistory of philosophy5031 Words   |  21 Pagesto): How can changes in philosophy be accounted for historically? What drives the development of thought in its historical context? To what degree can philosophical texts from prior historical eras be understood even today? All cultures — be they  prehistoric,  medieval, or  modern;  Eastern,  Western,  religious  or  secular  Ã¢â‚¬â€ have had their own unique schools of philosophy, arrived at through both inheritance and through independent discovery. Such theories have grown from different  premises  and approachesRead MoreOne Significant Change That Has Occurred in the World Between 1900 and 2005. Explain the Impact This Change Has Made on Our Lives and Why It Is an Important Change.163893 Words   |  656 Pagesepidemics. In no previous epoch of history was war so vilified and peace so consciously pursued through the establishment of international organizations and diplomatic exchanges. Despite these endeavors, the levels of domestic and international violence within human populations and the ravages visited upon animals and the natural world by humans vastly exceeded that of any previous era in history. In a century where human communities globally and individuals locally had the potential to be much more

A brief introduction to Frank Lloyd Wright Essay Example For Students

A brief introduction to Frank Lloyd Wright Essay Despite of all those negative critics, Wright proved his love for architecture and never even retired. He opened up an architectural school at his Taliesin West home and continued teaching architecture and built until the day he died in Arizona on April 9, 1959; he was ninety-two (Egger). Wright is now known as a true American architect who created many widely recognized structures, a number of them national landmarks even (Egger). Frank Lloyd Wright left behind a true legacy and survived all the criticism, coming out on top. He rightfully proved to the world that he was, and always will be, one of the greatest architects to ever live. It is obvious to see that Wright was one of the greatest architects to live. Just take a look at the number of things published on Wright and his work alone. There are hundreds, maybe even thousands of sources that provide information on him. For this essay on Wright, I used a variety of sources for my research. I used several books, one of which was Wrights autobiography, A Testament. The autobiography was very helpful in acquiring first hand accounts of Wrights life and work. The biographies I used were also helpful because they provided me with various views on different aspects of Wrights life and work. In Frank Lloyd Wright, Scully provided useful information about Wrights childhood influences. Many Masks: A Life of Frank Lloyd Wright by Gill provided me with similar information but gave some good quotes about Wright which were not found in the biography by Scully. Frank Lloyd Wright in Word and Form by Hertz also provided good quotes; however, these were quotes said by Wright himself rather than the biographer. The articles A Great Architect with Love for Nature and Lots of Fight by Secrest and The Many Lives of Frank Lloyd Wright by Pinck provided me with good comments about Wrights character. Frank Lloyd Wright: Innovator in American Architecture by Egger was very helpful with finding information on Wrights character as well, but also gave details on his personal life that were helpful in writing my paper. Frank Lloyd Wrights Humanism by Sandefur helped me find details on Wrights work, dealing with his love for nature and use of organic architecture. Wrights Path: Kids Blocks to Buildings was useful for the information it gave about Wrights influences as a young boy. When I initially began my research on Frank Lloyd Wright, I was finding a great number of resources, yet many of them were only about certain structures he had designed and built. The main reason I chose the sources that I did was because they provided not only information about his work, but also about his personal life and other things such as his architectural theories. One prominent architectural belief that Wright had was that organic architecture should be used to build any structure. Wright had very strong feelings about using the environment and natural resources to create architecture. He wanted to feel one with nature almost. He also wanted to create architecture that represented American democracy and provided people with a simple way of living that brought them closer to nature. Throughout my next essays, I will go into detail about those topics. I will discuss Wrights use of organic architecture and the criticism that he faced and how he overcame it to become the leading American architect of the twentieth century. I am certain that these topics on Wright will create a good persuasive essay and presentation. The research I have done so far has been successful. I have not encountered any major problems and have confidence in moving on to write the next two essays on Wright. Show preview only The above preview is unformatted text This student written piece of work is one of many that can be found in our University Degree Architecture section.